产品货号:
GS4603
中文名称:
重组小鼠C10/CCL6
英文名称:
Recombinant Murine Protein C10/CCL6
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 10.7kDa,a single non-glycosylated polypeptide chain containing 95 amino acids.
储存条件:冷冻(-20℃)
概述
Chemokine(C-C motif)ligand 6(CCL6),encoded by the gene CCL6,is a small cytokine belonging to the CC chemokine family that has only been identified in rodents.Murine CCL6 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF,M-CSF,IL-3 or IL-4 and has also been detected in an IL-2-dependent T cell line,where the expression is inhibited following T cell stimulation.It signals primarily through the CCR1 receptor.CCL6 is chemotactic for B cells,CD4+ T cells,monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors.The C10 contains the four highly conserved cysteine residues present in CC chemokines.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索:重组小鼠C10/CCL6,C10/CCL6, Murine,Recombinant Murine Protein C10/CCL6
储存条件:冷冻(-20℃)
概述
Chemokine(C-C motif)ligand 6(CCL6),encoded by the gene CCL6,is a small cytokine belonging to the CC chemokine family that has only been identified in rodents.Murine CCL6 is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF,M-CSF,IL-3 or IL-4 and has also been detected in an IL-2-dependent T cell line,where the expression is inhibited following T cell stimulation.It signals primarily through the CCR1 receptor.CCL6 is chemotactic for B cells,CD4+ T cells,monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors.The C10 contains the four highly conserved cysteine residues present in CC chemokines.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Fully biologically active when compared to standard.The biologically active determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100ng/ml. |
成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris,pH 8.0,500 mM NaCl. |
内毒素 | Less than 1 EU/μg of rMuC10/CCL6 as determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA |
相关搜索:重组小鼠C10/CCL6,C10/CCL6, Murine,Recombinant Murine Protein C10/CCL6